New research posits interesting links between gene expression and regions of the brain and BPD (Bipolar Disorder).
Researchers from the Lieber Institute for Brain Development along with researchers from John's Hopkins School of Medicine have pointed to two different gene expressions possibly pointing to BPD.
Scientists looked at two specific areas - the amygdala and the subgenual anterior cingulate cortex(sACC). These are both areas occupying the limbic system concerned with emotion and memory as well as several other functions.
The methodology is explained in the article given below. However, the outcome of the research was the realisation that miscommunication between neurons at the synaptic level (the gap over which information is passed between neurons) can influence BPD-like symptoms.
"This miscommunication manifests as severe swings in mood between depression and mania."